Fluoxetine hydropoforide CAS TSIS: {{{56296-78-7 yog lub ntiaj teb cov tshuaj tiv thaiv cov tshuaj tiv thaiv kev siv tshuaj tiv thaiv kab mob Lub tuam txhab yog thawj zaug kom ua tiav nws. 14 xyoos tom qab kev tshawb pom ntawm fluoxetine, xyoo 1986, Belgium ua ntej tau pom zoo nws cov npe tshuaj rau kev kho mob. Thaum kawg ntawm 1987, nws tau pom zoo los ntawm FDA nkag mus rau Asmeskas kev ua lag luam nyob rau hauv lub npe lag luam Prozac. Nws tau los ua cov tshuaj tiv thaiv zoo tshaj plaws hauv Asmeskas thiab kev tawm tsam lub sijhawm tshiab ntawm kev nyuaj siab thiab kev nyab xeeb zoo. Tom qab ntawd tom qab ntawd teev nyob rau ntau lub tebchaws Western xws li United Kingdom thiab Fabkis, thiab tam sim no tau muag hauv qab.
Vim tias Fluoxetine yog thawj 5- HT} HT} HT} HT ເpressກ ເ fromັກ ເ from mechan້ນ ເ marketັກ thiab Cov Qauv Hluav Taws Xob Nws tau paub cov txiaj ntsig zoo thiab cov kev mob me. Nws tau muaj kev npau taws tom qab nws mus rau tom khw, thiab nws cov muag tau nce xyoo dhau los ntawm xyoo. Txij li cov kev tshawb fawb thiab kev nthuav dav ntawm Fluoxetine los ntawm Eli Lilly nyob rau xyoo 1970 tau raug hu ua ib tiam neeg tshiab thiab qhib tshooj tshiab hauv kev kho mob. Txawm hais tias kev ua lag luam tau tsis kam tom qab xyoo 2001, nws yog ib qho ntawm cov tshuaj feem ntau siv rau kev kho mob antidepressant.
Fluoxetine tuaj yeem thaiv 5- HT2A cov receptors thiab rov ua da dej thiab tsis nyob hauv {2}} HT2a receptors. Nyob rau tib lub sijhawm, Fluoxetine kuj tseem tuaj yeem tso cov kev cuam tshuam ntawm Ne thiab Da los ntawm -aminobutyric acid (Gaba) Neurons los ntawm {5}} HT2C receptor. Ntxiv rau kev nce qib {5- hem siab nyob rau hauv lub synaptic cleft, nws yog tus yam ntxwv ntawm n thiab da de-inhibition (nddi).
Fluoxetine hydropegide tsis tsuas yog siv rau ntau hom kev nyuaj siab, nws yog qhov tsim nyog tshwj xeeb rau cov tsos mob kev nyuaj siab txuam nrog cov kab mob organic thiab kev nyuaj siab. Nws tseem siv los kho kev nyuaj siab tom qab schizophrenia. Nws kuj tseem siv rau kev ntxhov siab obsive, Phobia, kev ntxhov siab ntawm kev ntxhov siab, kev kho kom yuag thiab ua qhov kev txiav luam yeeb.
